Причина падения
$VRTX :
Feeling the pain at Vertex
The drug company made an announcement on a promising candidate treatment for a rare disease that disappointed investors.
Vertex had been hoping that its VX-814 drug would be able to treat a disease called alpha-1 antitrypsin deficiency. The disease is inherited based on genetic profile, and it can cause damage to the liver and lungs, resulting in lung diseases such as emphysema as well as jaundice and advanced liver disease.
A phase 2 study had been looking at patients suffering from this disease, but Vertex had to discontinue that study based on safety indicators and early data on the patients' reactions to the drug. With elevated liver enzymes appearing, Vertex decided no longer to pursue treating the disease with VX-814.
Vertex does have another candidate drug, VX-864, that it hopes will prove more promising. A phase 2 trial is ongoing with that treatment with data expected in the first half of 2021. For now, though, investors are mourning the loss of a hoped-for solution to a rare genetic disease.